Dendritic Cells Transduced with Obtained by In Vitro Stimulation with Recognized by Cytolytic T Lymphocytes Identification of Five MAGE-A1 Epitopes
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منابع مشابه
Identification of five MAGE-A1 epitopes recognized by cytolytic T lymphocytes obtained by in vitro stimulation with dendritic cells transduced with MAGE-A1.
MAGE genes are expressed by many human tumors of different histological types but not by normal cells, except for male germline cells. The Ags encoded by MAGE genes and recognized by T cells are therefore strictly tumor-specific. Clinical trials involving therapeutic vaccination of cancer patients with MAGE antigenic peptides or proteins are in progress. To increase the range of patients eligib...
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تاریخ انتشار 1999